CONTINUOUS FLOW VENTILATION WITHOUT RESPIRATORY MOVEMENT IN CAT, DOG AND HUMAN

Abstract
The insufflation of oxygen at 1 litre kg−1 min−1 via two endobronchial catheters (called continuous flow ventilation (CFV)) maintained a normal Paco2 and a constant Pao2 in anaesthetized paralysed dogs and in five out of seven cats. In two cats with a high carbon dioxide production, CFV failed to maintain carbon dioxide homeostasis since gas flows greater than 1 litre kg−1 min−1 caused thoracic distension and a decrease in arterial pressure. In five patients, endobronchial insufflation of oxygen 0.5 litre kg−1 min−1 caused approximately a 30% decrease in the increase in Paco2 compared with apnoeic oxygenation (P < 0.05) during a period of 6 min. CFV at 1 litre kg−1 min−1 can be used for physiological measurement without respiratory movement while maintaining blood-gas homeostasis in dogs and in cats with a normal carbon dioxide production. Ethical constraints have so far prevented the investigation of the effects of comparable gas flows in man.

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