CONTINUOUS FLOW VENTILATION WITHOUT RESPIRATORY MOVEMENT IN CAT, DOG AND HUMAN
Open Access
- 1 May 1986
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 58 (5) , 544-550
- https://doi.org/10.1093/bja/58.5.544
Abstract
The insufflation of oxygen at 1 litre kg−1 min−1 via two endobronchial catheters (called continuous flow ventilation (CFV)) maintained a normal Paco2 and a constant Pao2 in anaesthetized paralysed dogs and in five out of seven cats. In two cats with a high carbon dioxide production, CFV failed to maintain carbon dioxide homeostasis since gas flows greater than 1 litre kg−1 min−1 caused thoracic distension and a decrease in arterial pressure. In five patients, endobronchial insufflation of oxygen 0.5 litre kg−1 min−1 caused approximately a 30% decrease in the increase in Paco2 compared with apnoeic oxygenation (P < 0.05) during a period of 6 min. CFV at 1 litre kg−1 min−1 can be used for physiological measurement without respiratory movement while maintaining blood-gas homeostasis in dogs and in cats with a normal carbon dioxide production. Ethical constraints have so far prevented the investigation of the effects of comparable gas flows in man.This publication has 2 references indexed in Scilit:
- Effect of heart rate and stroke volume on gas mixing in dog lungJournal of Applied Physiology, 1982
- Constant-flow ventilation of apneic dogsJournal of Applied Physiology, 1982