Cholesterotic fibrous histiocytoma. Its association with hyperlipoproteinemia

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Abstract
A 63-year-old woman with fibrous histocytomas showed cholesterol deposition in the setting of type IIB hyperlipidemia. The two lesions involved the left leg and right thigh. One had typical features of a fibrous histiocytoma including changes of the overlying epidermis. The other was essentially replaced by cholesterol deposits and could not be differentiated from a tuberous xanthoma. This case illustrates the histiocytic responses of fibrous histiocytomas to a hyperlipoproteinemic microenvironment.