Identification in Rabbit Urine of the 3-Glucuronoside-17-N-acetylglucosaminide of 17α-Estradiol
- 1 April 1965
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 76 (4) , 600-603
- https://doi.org/10.1210/endo-76-4-600
Abstract
Four rabbits were given large doses of estrone benzoate subcutaneously and a tracer dose of 16-14C-estrone intravenously. Extraction of the urine with butanol yielded a major radioactive product which was identified as the 3-glucuronoside-17α-N-acetylglucosaminide of estradiol. This confirms the indications of previous work that the rabbit excretes 17α-estradiol as a double glycoside. (Endocrinology76: 600, 1965)Keywords
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