No evidence for linkage of chromosome 6p markers to schizophrenia in Southern African Bantu-speaking families
- 1 January 1996
- journal article
- research article
- Published by Wolters Kluwer Health in Psychiatric Genetics
- Vol. 6 (2) , 41-50
- https://doi.org/10.1097/00041444-199622000-00003
Abstract
Previous studies have yielded evidence for a locus conferring susceptibility to schizophrenia and schizophrenia spectrum disorders on chromosome 6p24–22 in a sample of multiply affected Irish families. We tested for linkage between highly polymorphic chromosome 6p24–22 markers and narrowly defined schizophrenia in a sample of 19 Southern African Bantu-speaking families, a population known to have diverged in the last 2000 years. There is no evidence to support the linkage of markers in this region of chromosome 6 to schizophrenia in this population.Keywords
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