Effect of chain length of short-chain fatty acids on their effect on intracranial pressure in rabbits
Open Access
- 1 May 1982
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 45 (5) , 428-430
- https://doi.org/10.1136/jnnp.45.5.428
Abstract
The short-chain fatty acids propionic, butyric, valeric, isovaleric and octanoic produced elevations in intracranial pressure during intravenous infusion in rabbits. Serum concentrations of these compounds are elevated in patients with Reye's syndrome, and may contribute to the intracranial pressure elevations found in these patients.This publication has 14 references indexed in Scilit:
- Short chain fatty acid‐induced central hyperventilation in rabbitsNeurology, 1978
- Biochemical correlates of illness and recovery in Reye's syndromeAnnals of Neurology, 1977
- Short‐chain organic acidemia and Reye's syndromeNeurology, 1975
- Isovaleric and α-Methylbutyric Acidemias Induced by Hypoglycin A: Mechanism of Jamaican Vomiting SicknessScience, 1972
- Encephalopathy and Fatty Degeneration of the Viscera: A Clinicopathologic Analysis of 40 CasesAmerican Journal of Clinical Pathology, 1971
- Propionic acidemia in patients with ketotic hyperglycinemiaThe Journal of Pediatrics, 1971
- Isovaleric AcidemiaNew England Journal of Medicine, 1967
- Isovaleric acidemia: a new genetic defect of leucine metabolism.Proceedings of the National Academy of Sciences, 1966
- Induction of swelling of liver mitochondria by fatty acids of various chain lengthBiochimica et Biophysica Acta, 1963
- ENCEPHALOPATHY AND FATTY DEGENERATION OF THE VISCERA A DISEASE ENTITY IN CHILDHOODThe Lancet, 1963