Fruit flies with additional expression of the elongation factor EF-1 alpha live longer.
- 1 October 1989
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 86 (19) , 7520-7521
- https://doi.org/10.1073/pnas.86.19.7520
Abstract
In Drosophila melanogaster, the decrease in protein synthesis that accompanies aging is preceded by a decrease in elongation factor EF-1.alpha. protein and mRNA. Here we show that Drosophila transformed with a P-element vector containing an EF-1.alpha. gene under control of hsp70 regulatory sequences have a longer life-span than control flies.This publication has 14 references indexed in Scilit:
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