On the Role of the Nitrogen Atom in Dynemicin A
- 1 January 1995
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1995 (01) , 38-40
- https://doi.org/10.1055/s-1995-4851
Abstract
The dynemicin analogs 13a,b have been synthesized from the cyclohexenone derivative 8b via the enediyne aldehyde 12. NMR analysis indicates that 13a,b exist as rotamers around the C-aryl bond. This points to the role of the nitrogen atom in dynemicin A for fixation of the conformation of the aryl ring.Keywords
This publication has 0 references indexed in Scilit: