Mixed Lymphocyte Reactions: Augmentation by Drugs That Inhibit Stimulator Cell Protein Synthesis
Open Access
- 1 October 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 117 (4) , 1295-1299
- https://doi.org/10.4049/jimmunol.117.4.1295
Abstract
Inhibiting the protein synthesis of F1 stimulator cells in a mixed lymphocyte reaction (MLR) can enhance the DNA synthetic response and cytotoxic activity of the responder parental lymphocytes, independent of the number of stimulator cells used. Thus stimulator lymphocytes act not only as a source of antigen but play an additional regulatory role in the MLR.This publication has 0 references indexed in Scilit: