New approaches to the synthesis of β-lactam antibiotics
- 1 January 1987
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 6,p. 1237-1242
- https://doi.org/10.1039/p19870001237
Abstract
The selective syntheses of carbapenams and carbacephams are described from the same intermediate by application of appropriate experimental conditions using radical cyclisation techniques. The carbapenams were synthesised diastereoselectively by a 5-exo trig cyclisation.This publication has 8 references indexed in Scilit:
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