Autoradiography of chromosomal DNA fibers from Chinese hamster cells.
- 1 March 1966
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 55 (3) , 599-606
- https://doi.org/10.1073/pnas.55.3.599
Abstract
Linear DNA autoradiograms are found when the Cairns technique is applied to Chinese hamster cells. At least 6% of these autoradiograms are more than 0.8 mm long-roughly the size of the Escherichia coli chromosome and considerably longer than previously reported DNA fibers from higher organisms. Some rare autoradiograms are as long as 1.6-1.8 mm. The implications of these results in terms of models of chromosome structure are disc ussed.This publication has 16 references indexed in Scilit:
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