THE RELATION OF ENDOCRINE FUNCTION TO RESISTANCE AND IMMUNITY. II. THE INDEPENDENCE OF CEVITAMIC ACID AND COMPLEMENT FOLLOWING ALTERATIONS IN THYROID FUNCTION IN THE RABBIT

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Abstract
The changes of complement conc. accompanying alterations in thyroid activity in the rabbit, reported in the previous paper, were independent of the cevitamic acid level of the blood. In 7 thyroidec-tomized rabbits the complement conc. of the blood serum fell even though the cevitamic acid level was maintained within normal levels. The rise in complement conc. in 4 rabbits made thyrotoxic occurred in spite of an almost complete disappearance of cevitamic acid from the blood. The contrast between this observed independence of the levels of the 2 substances in the blood serum in the rabbit and the reported dependence in the guinea pig is discussed.