THREE TYPES OF HUMAN DIABETES

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Abstract
Three types of human diabetes all showing hyperglycemia and glyco-suria, described and differentiated on grounds of excess or lack of stored body fat, and by the presence or absence of ketosis, and (2) by the different amounts of active insulin in their blood or extractable from the pancreas after death. Lipoplethoric diabetes, the commonest form, is found in the obese middle aged, without ketosis and with a normal, or nearly normal, blood and pancreatic insulin content. Reducing diet controls the condition. Insulin deficient diabetes is also a common form, especially in the young, with loss of weight, heavy ketosis, no plasma insulin and little pancreatic insulin. Insulin treatment is essential. Lipo-atrophic diabetes: Five cases of this very rare syndrome in young people are described. It is differentiated clinically by complete absence of body fat, and by hyperlipemia, hepatomegaly, and a high basal metabolic rate.

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