Abstract
Evidence indicates that disturbed circulation in the spinal cord is one factor in the production of paralysis in poliomyelitis. More than 95% of cases have at least 1 extremity that escapes paralysis. If an extremity is at all involved, > 2/3 of its muscles become paralyzed. All of the anterior horn cells appear to be affected together, and the paralysis depends upon intrinsic factors including circulatory changes. The circulatory changes explain the localization of the paralysis. Methods, such as the paraver-tebral block, which attempt to alter spinal cord circulation, are being investigated.

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