STUDIES ON HUMAN ADRENAL STEROIDS: 2. ISOLATION OF 20α-DIHYDROCORTICOSTERONE FROM THE PLASMA OF NORMAL MALES TREATED WITH CORTICOSTERONE
- 1 January 1958
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry and Physiology
- Vol. 36 (1) , 819-823
- https://doi.org/10.1139/y58-087
Abstract
Five fasting normal male humans were infused intravenously with 200 mg. of corticosterone. Blood samples were then withdrawn at various time intervals and the plasma was analyzed for individual Δ4-3-keto C21 adrenal steroids. In each case 20α-dihydrocorticosterone appeared as a metabolite. The isolated corticosterone and 20α-dihydrocorticosterone were characterized chemically and quantitative plasma levels of each are reported.Keywords
This publication has 1 reference indexed in Scilit:
- THE SECRETION OF CORTISOL AND CORTICOSTERONE BY THE HUMAN ADRENAL CORTEXActa Endocrinologica, 1957