Genetic Associations of Transitional Cell Carcinoma
- 1 April 1979
- journal article
- Published by Wiley in British Journal of Urology
- Vol. 51 (2) , 73-77
- https://doi.org/10.1111/j.1464-410x.1979.tb02835.x
Abstract
A series of 101 cases of transitional cell carcinoma (TCC) was contrasted with a control series for several genetic parameters. Three genetic associations were demonstrated with the TCC patients having A gene frequencies, HLA B5 and HLA CW4 genes all higher than might be expected by chance. A classification of the natural history of the disease is used to show that the HLA frequencies vary with the more or the less severe forms of the disease.Keywords
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