PATHOGENESIS OF STAPHYLOCOCCUS-AUREUS MASTITIS - BACTERIOLOGIC, HISTOLOGIC, AND ULTRASTRUCTURAL PATHOLOGIC FINDINGS

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  • 1 January 1984
    • journal article
    • research article
    • Vol. 45  (12) , 2525-2531
Abstract
Three lactating cows were experimentally infected with S. aureus ATCC 2940 (Newbould 305 strain). Cows were euthanatized 2-216 h after inoculation. Bacteriologic and microscopic examinations showed that S. aureus attached to epithelial cells of the mammary gland in vivo. The histopathologic changes observed were progressive swelling, vacuolar degeneration of epithelial layers and multiple foci for epithelial erosions and ulcers throughout the ductal system. The cellular response of the infected glands was demonstrated by a rapid increase in the number of somatic cells in the secretion and by accumulation of neutrophils below, within and on the epithelium of the teat and lactiferous sinuses. The inflammatory response did not prevent infecion nor subsequent pathologic changes in the inoculated glands.