POSTVACCINAL ENCEPHALITIS AND ALLIED CONDITIONS

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Abstract
In 1923 I had the privilege, as Frederick A. Packard lecturer, of addressing the College of Physicians on a subject related to the present one. Some may recall that the Packard lecture was devoted to a consideration, chiefly from the standpoint of the pathologic changes, of the disease called indifferently "lethargic" and "epidemic encephalitis." The effort made in that lecture was to define the disease in as clear a manner as was possible at the time, and to separate it from certain pathologic and clinical complexes with which it had been brought into alliance. What was really undertaken, and perhaps accomplished, was to distinguish epidemic encephalitis from epidemic influenza, Australian X-disease, herpes virus encephalitis, and even from epidemic poliomyelitis. The net result of this analysis was to present epidemic encephalitis as a clinical and pathologic complex of independent nature, the etiology of which still remained undetermined. In 1923, epidemics of

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