Correlative Rise and Fall of Glucose in Blood Plasma and Dental Pulp Fluid

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Abstract
A hole was drilled to the pulp chamber of the molar teeth of anesthetized dogs and a capillary glass tube inserted and sealed in place for collection of the dental pulp fluid. The pulp is not injured with the technique employed. Blood samples were obtained from the saphenous vein for analysis of glucose in the plasma. After the basal values of the sugar in the blood plasma and in the dental pulp fluid were obtained, the blood sugar level was raised and maintained at a high level by continuous intravenous infusion of a glucose solution. Similarly, the blood sugar level was lowered by infusion of insulin. When pulp fluid had accumulated in the capillary tube in an amount sufficient for analysis, a blood sample was taken. The rise in the blood sugar level produced by infusion of glucose was accompained by a concomitant rise in the sugar concentration in the dental pulp fluid. Conversely, the drop in the blood sugar level produced by the infusion of insulin was accompanied by a corresponding reduction in the sugar concentration in the pulp fluid.

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