AN ANALYSIS OF ABLATION OF THYROID REMNANTS WITH I-131 IN 511 PATIENTS FROM 1947-1984 - EXPERIENCE AT UNIVERSITY-OF-MICHIGAN

  • 1 January 1984
    • journal article
    • research article
    • Vol. 25  (12) , 1287-1293
Abstract
Between Jan. 1947 and June 1983, 511 patients were given treatment doses of 131I after surgery for thyroid cancer in the presence of 131I uptake in thyroid remnants. Patients (34) were removed from the study leaving 462 patients with a 99% follow-up at 1 or more yr, with a mean follow-up of 15 yr. Of 267 patients with radioiodine uptake confined to the thyroid bed, 233 (87%) had ablation from the 1st dose of 131I ranging from 100 to > 200 mCi. The higher the percent uptake, the more difficult it was to achieve ablation. In the percentages of successful ablation, there were no significant differences between 131I doses of: 100-149 mCi, 150-174 mCi, 179-199 mCi and 200 mCi or more. The 100-149 mCi ablative dose may furnish adjuvant therapy for occult metastases.

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