INTRA-ARTICULAR HYDROCORTISONE IN THE TREATMENT OF ARTHRITIS
- 30 September 1953
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 39 (4) , 735-746
- https://doi.org/10.7326/0003-4819-39-4-735
Abstract
A total of 8693 intrasynovial injns. of hydrocortisone were given to 852 patients for local therapy for various types of rheumatic disease, mainly arthritis. At least partial and temporary amelioration of local symptoms and signs, often persisting for weeks or months, was noted after nearly 85% of injns. Adverse effects from locally administered hydrocortisone occurred in only 2.3%, and were nearly always mild and self limited. Indications and contraindications are discussed. This method is regarded as a local adjunct in the treatment of arthritis, and does not replace approved systemic therapy for such conditions. For such localized conditions as bursitis, traumatic tenosynovitis, and sprains it may be employed successfully alone. Systemic side effects from this method of hormone admn. have not been noted.Keywords
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