The sequence, and its evolutionary implications, of a Thermococcus celer protein associated with transcription.
- 26 April 1994
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 91 (9) , 3854-3856
- https://doi.org/10.1073/pnas.91.9.3854
Abstract
Through random search, a gene from Thermococcus celer has been identified and sequenced that appears to encode a transcription-associated protein (110 amino acid residues). The sequence has clear homology to approximately the last half of an open reading frame reported previously for Sulfolobus acidocaldarius [Langer, D. & Zillig, W. (1993) Nucleic Acids Res. 21, 2251]. The protein translations of these two archaeal genes in turn are homologs of a small subunit found in eukaryotic RNA polymerase I (A12.2) and the counterpart of this from RNA polymerase II (B12.6). Homology is also seen with the eukaryotic transcription factor TFIIS, but it involves only the terminal 45 amino acids of the archaeal proteins. Evolutionary implications of these homologies are discussed.Keywords
This publication has 19 references indexed in Scilit:
- Structure of the gene encoding the 14.5 kDa subunit of human RNA polymerase IINucleic Acids Research, 1993
- Basic local alignment search toolJournal of Molecular Biology, 1990
- HMf, a DNA-binding protein isolated from the hyperthermophilic archaeon Methanothermus fervidus, is most closely related to histones.Proceedings of the National Academy of Sciences, 1990
- Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya.Proceedings of the National Academy of Sciences, 1990
- Drosophila RNA polymerase II elongation factor DmS-II has homology to mouse S-II and sequence similarity to yeast PPR2Nucleic Acids Research, 1990
- Archaebacterial DNA-dependent RNA polymerases testify to the evolution of the eukaryotic nuclear genome.Proceedings of the National Academy of Sciences, 1989
- Bacterial evolution.1987
- Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.Proceedings of the National Academy of Sciences, 1983
- DNA sequencing with chain-terminating inhibitorsProceedings of the National Academy of Sciences, 1977
- A complementation analysis of the restriction and modification of DNA in Escherichia coliJournal of Molecular Biology, 1969