OBSERVATIONS ON DENTAL ANAESTHESIA INTRODUCED WITH METHOHEXITONE I: INDUCTION OF ANAESTHESIA

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Abstract
Observations have been made on 2,000 patients undergoing dental surgery under general anaesthesia in the sitting position. The anaesthetic sequence consisted of a single dose of methohexitone—mean dose, male 10.8 mg/stone (1.7 mg/kg), female 7.5 mg/stone (1.18 mg/kg); range, male 4–20 mg/stone (0.63–3.14 mg/kg), female 2–16 mg/stone (0.31–2.51 mg/kg)—followed by nitrous oxide and oxygen. Halothane was also used in 30 per cent of patients as a supplement. (Inspired concentration approximately 1 per cent.) The incidence of observed fainting at the beginning of induction was 1 in 500. The advantages and disadvantages of using relatively large doses of methohexitone are outlined and a method of overcoming the problem of respiratory depression immediately following the barbiturate is described. It is stressed that techniques using larger doses of methohexitone should be used only by those familiar with the application of controlled respiration.

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