PROGNOSIS IN THREATENED-ABORTION EVALUATED BY HORMONE ASSAYS AND ULTRASOUND SCANNING

  • 1 January 1980
    • journal article
    • research article
    • Vol. 55  (4) , 435-438
Abstract
The prognosis for patients admitted with threatened abortion on the basis of assays of serum estradiol (E2) and progesterone (P) and the demonstration of fetal heart movements (FHM) by ultrasound scanning was estimated. Of the 97 patients included in the study, 35% (with 95% confidence limits 25-45%) aborted spontaneously. Of the patients with normal serum E2 and P levels, 88% (74-96%) and 91% (79-98%), respectively, continued to term whereas 52% (39-66%) and 58% (44-72%), respectively, with pathologic levels aborted. Ultrasound scanning for FHM exhibited the greatest diagnostic accuracy: 92% of the patients (83-97%) with FHM at the 1st scan carried to term and 91% (75-98%) without FHM aborted. After 9 wk gestation, the recording of FHM, if any, was reliable in 100% of the cases. Ultrasound scanning with determination of FHM is evidently of greater prognostic value than hormone assays in patients with threatened abortion.

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