Mapping of DNA topoisomerase II poisons (etoposide, clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle
- 1 April 1996
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 51 (7) , 879-886
- https://doi.org/10.1016/0006-2952(95)02241-4
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- DNA Topoisomerases: Essential Enzymes and Lethal TargetsAnnual Review of Pharmacology and Toxicology, 1994
- Antagonistic effect of the cardioprotector (+)-1,2-BIS(3,5-dioxopiperazinyl-1-YL)propane(ICRF-187) on dna breaks and cytotoxicity induced by the topoisomerase ii directed drugs daunorubicin and etoposide (VP-16)Biochemical Pharmacology, 1993
- Different modes of anthracycline interaction with topoisomerase II: Separate structures critical for DNA-cleavage, and for overcoming topoisomerase II-related drug resistanceBiochemical Pharmacology, 1993
- Mode of action of topoisomerase II-targeting agents at a specific DNA sequence: Uncoupling the DNA binding, cleavage and religation eventsJournal of Molecular Biology, 1992
- Effects of antineoplastic drugs on the post-strand-passage DNA cleavage/religation equilibrium of topoisomerase IIBiochemistry, 1991
- Characterization of an Amsacrine-resistant Line of Human Leukemia CellsJournal of Biological Chemistry, 1989
- Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26Biochemistry, 1988
- H2O2 as a DNA fragmenting agent in the alkaline elution interstrand crosslinking and DNA-protein crosslinking assaysAnalytical Biochemistry, 1988
- Inhibition of epipodophyllotoxin cytotoxicity by interference with topoisomerase-mediated DNA cleavageBiochemical Pharmacology, 1985
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976