Acute HIV Infection Induces Mucosal Infiltration With CD4+ and CD8+ T Cells, Epithelial Apoptosis, and a Mucosal Barrier Defect
- 1 October 2010
- journal article
- Published by Elsevier in Gastroenterology
- Vol. 139 (4) , 1289-1300.e2
- https://doi.org/10.1053/j.gastro.2010.06.065
Abstract
No abstract availableKeywords
Funding Information
- Deutsche Forschungsgemeinschaft
- Deutsche Forschungsgemeinschaft
This publication has 43 references indexed in Scilit:
- Impairment of the intestinal barrier is evident in untreated but absent in suppressively treated HIV-infected patientsGut, 2008
- Metabolic and Immune Activation Effects of Treatment Interruption in Chronic HIV-1 Infection: Implications for Cardiovascular RiskPLOS ONE, 2008
- Immune modulators and treatment interruptionCurrent Opinion in HIV and AIDS, 2008
- Rapid Onset of Intestinal Epithelial Barrier Dysfunction in Primary Human Immunodeficiency Virus Infection Is Driven by an Imbalance between Immune Response and Mucosal Repair and RegenerationJournal of Virology, 2008
- Microbial translocation is a cause of systemic immune activation in chronic HIV infectionNature Medicine, 2006
- Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infectionNature, 2005
- CD4 T Cell Depletion Is Linked Directly to Immune Activation in the Pathogenesis of HIV-1 and HIV-2 but Only Indirectly to the Viral LoadThe Journal of Immunology, 2002
- Identifying the Target Cell in Primary Simian Immunodeficiency Virus (SIV) Infection: Highly Activated Memory CD4+T Cells Are Rapidly Eliminated in Early SIV Infection In VivoJournal of Virology, 2000
- Rapid mucosal CD4+ T-cell depletion and enteropathy in simian immunodeficiency virus–infected rhesus macaquesGastroenterology, 1999
- Duodenal biopsies of HIV-infected patients with diarrhoea exhibit epithelial barrier defects but no active secretionAIDS, 1998