Preparation of Ethyl Hypophosphite1,2
- 1 January 1979
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 9 (6) , 535-538
- https://doi.org/10.1080/00397917908060957
Abstract
We report a convenient synthesis of ethyl hypophosphite by the O-alkylation of sodium hypophosphite (eq 1). Thus, when sodium hypo-phosphite is allowed to react with triethyloxonium tetrafluoroborate in methylene chloride at 0°, simple filtration from the inorganic salts and evaporation of the solvent gives the pure ester in 80% yield. This simple preparation employs readily available starting materials3.Keywords
This publication has 4 references indexed in Scilit:
- Transesterification of alkyl phosphinatesJournal of the Chemical Society, Chemical Communications, 1978
- Synthesis of Hypophosphite Esters from Orthocarbonyl CompoundsJournal of the American Chemical Society, 1964
- Hyophosphorous (phosphinic) estersRussian Chemical Bulletin, 1960
- Über Tertiäre Oxoniumsalze, IIJournal für Praktische Chemie, 1939