Agonist-like character of the (R)-enantiomer of 1-hydroxy-3-amino-pyrrolid-2-one (HA-966)
- 12 September 1991
- journal article
- Published by Elsevier in European Journal of Pharmacology: Molecular Pharmacology
- Vol. 208 (1) , 25-29
- https://doi.org/10.1016/0922-4106(91)90047-l
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Stereoselectivity for the (R)‐Enantiomer of HA‐966 (l‐Hydroxy‐3‐Aminopyrrolidone‐2) at the Glycine Site of the N‐Methyl‐d‐Aspartate Receptor ComplexJournal of Neurochemistry, 1990
- Pharmacological characteristics of cyclic homologues of glycine at the N-methyl-d-aspartate receptor-associated glycine siteNeuropharmacology, 1990
- The Glycine Site of the N‐Methyl‐D‐Aspartate Receptor Channel: Differences Between the Binding of HA‐966 and of 7‐Chlorokynurenic AcidJournal of Neurochemistry, 1990
- Evidence for a functional coupling of the NMDA and glycine recognition sites in synaptic plasma membranesEuropean Journal of Pharmacology: Molecular Pharmacology, 1990
- HA-966 antagonizes N-methyl-D-aspartate receptors through a selective interaction with the glycine modulatory siteJournal of Neuroscience, 1989
- 1‐Aminocyclopropane Carboxylic Acid: A Potent and Selective Ligand for the Glycine Modulatory Site of the N‐Methyl‐d‐Aspartate Receptor ComplexJournal of Neurochemistry, 1989
- 1-Aminocyclopropane-1-carboxylic acid (ACC) mimics the effects of glycine on the NMDA receptor ion channelEuropean Journal of Pharmacology, 1988
- 6,7-Dinitro-quinoxaline-2,3-dion and 6-nitro,7-cyano-quinoxaline-2,3-dion antagonise responses to NMDA in the rat spinal cord via an action at the strychnine-insensitive glycine receptorEuropean Journal of Pharmacology, 1988
- Glycine reverses antagonism of N-methyl-D-aspartate (NMDA) by 1-hydroxy-3-aminopyrrolidone-2 (HA-966) but not by D-2-amino-5-phophonovalerate (D-AP5) on rat cortical slicesEuropean Journal of Pharmacology, 1988
- New quinoxalinediones show potent antagonism of quisqualate responses in cultured mouse cortical neuronsNeuroscience Letters, 1988