A selective concentration-dependent dysrhythmogenic and antidysrhythmic action of prostaglandins E2, F2α and I2 (prostacyclin) on isolated rat hearts
- 1 August 1980
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 36 (8) , 996-998
- https://doi.org/10.1007/bf01953843
Abstract
Prostaglandins (PGs) E2, F2α, and I2 were examined for their effects on the electrical and mechanical activities of isolated rat, rabbit and guinea-pig hearts. All PGs produced dysrhythmias in rat hearts at low concentrations only, while higher concentrations were antiarrhythmic. Guinea-pig hearts were less responsive while rabbit hearts were completely resistant.This publication has 12 references indexed in Scilit:
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