Histocompatibility Antigens in Alzheimer’s Disease

Abstract
A preliminary study of Alzheimer''s disease showed an apparent excess of the antigen HLA-A2 in patients who presented the disease before the age of 60: those with onset after 64 showed different frequencies of the antigens HLA-A1 and A3 when compared with the local population. There was no abnormality in the distribution of HLA-B locus antigens. The findings are briefly discussed.

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