Triple-quantum-coherence-filtered imaging of sodium ions in vivo at 4.7 tesla
- 1 February 1990
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 13 (2) , 305-313
- https://doi.org/10.1002/mrm.1910130213
Abstract
The tissue distribution of sodium ions which generate triple‐quantum coherence (TQC) in vivo is determined from images. A technique for filtering conventional sodium images, so that signal is obtained only from sodium ions which have a correlation time appropriate for producing TQC, is described. The utility of TQC‐filtered sodium images is demonstrated in a study of tumors implanted in a nude rat model, where the intensity of the TQC signal from sodium ions in the growing margin of the tumor is observed to be 200‐250% greater than that from surrounding tissue.This publication has 8 references indexed in Scilit:
- Two-dimensional double-quantum NMR spectroscopy of isolated spin 3/2 systems: sodium-23 examplesJournal of the American Chemical Society, 1988
- Experimental and human brain neoplasms: detection with in vivo sodium MR imaging.Radiology, 1987
- Clinical and experimental vasogenic edema: in vivo sodium MR imaging. Work in progress.Radiology, 1986
- Sodium nuclear magnetic resonance imaging of myocardial tissue of dogs after coronary artery occlusion and reperfusionJournal of the American College of Cardiology, 1986
- NMR relaxation studies of intracellular Na+ in red blood cellsBiophysical Chemistry, 1984
- Quadrupolar relaxation. The multiquantum coherencesThe Journal of Physical Chemistry, 1981
- MONOVALENT ION FLUXES AND THE CONTROL OF CELL PROLIFERATION IN CULTURED FIBROBLASTSAnnals of the New York Academy of Sciences, 1980
- Increased sodium ion influx is necessary to initiate rat hepatocyte proliferationCell, 1979