Preparative high-performance liquid chromatography on chemically modified porous glass. Isolation of saponins from ginseng.
- 1 January 1990
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 38 (6) , 1630-1632
- https://doi.org/10.1248/cpb.38.1630
Abstract
Preparative high-performance liquid chromatography on octadecylisilyl porous glass (pore size, 550Å) with acetonitrile-water as the mobile phase was applied for the isolation of saponins from Panax ginseng. In a single run, several milligrams of pure ginsenosides were obtained from 10g of roots of Panax ginseng. The method was simple, rapid and convenient and should be applicable to isolation of other saponins of crude drugs.Keywords
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