The metabolism of14C-labelled trimethylamine and itsN-oxide in man
- 1 January 1987
- journal article
- research article
- Published by Taylor & Francis in Xenobiotica
- Vol. 17 (5) , 551-558
- https://doi.org/10.3109/00498258709043962
Abstract
1. The metabolism and elimination of 14C-labelled trimethylamine and its N-oxide (100 mg orally) were studied in three male volunteers. 2. For both compounds the urine was the major route of elimination, with 95% of the administered 14C being voided in the first 24 h. No radioactivity was found in expired air. 3. The majority (> 95%) of the urinary 14C from both compounds was excreted as trimethylamine N-oxide.This publication has 21 references indexed in Scilit:
- The genetic control of sparteine and debrisoquine metabolism in man with new methods of analysing bimodal distributions.Journal of Medical Genetics, 1983
- The metabolism of benodanil in the ratPesticide Science, 1981
- Trimethylamine N-oxide synthesis: A human variantBiochemical Medicine, 1972
- The analysis of nicotine-1‘-N-oxide in urine, in the presence of nicotine and cotinine, and its application to the study of in vivo nicotine metabolism in manJournal of Pharmacy and Pharmacology, 1971
- The Fate of Trimethylamine Oxide and Trimethylamine in ManJournal of the Fisheries Research Board of Canada, 1941
- Untersuchungen über die Organextrakte der SelachierPflügers Archiv - European Journal of Physiology, 1909
- Das Trimethylamin als normales Produkt des Stoffwechsels, nebst einer Methode für dessen Bestimmung im Harn und Kot.Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1906
- Trimethylamin aus MenschenharnEuropean Journal of Organic Chemistry, 1856
- Ueber das Vorkommen von Propylamin in den Blüthen von Crataegus oxyacanthaEuropean Journal of Organic Chemistry, 1854
- Beiträge zur Kenntniss der flüchtigen organischen BasenEuropean Journal of Organic Chemistry, 1851