Preparation of Protected β-Keto Aldehydes from β-Keto Esters via Selective Reduction of Acyl(alkoxycarbonyl)ketene Dithioacetals
- 1 January 1988
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1988 (10) , 792-794
- https://doi.org/10.1055/s-1988-27709
Abstract
The acyl(alkoxycarbonyl)ketene dithioacetals 2 prepared from the corresponding ß-keto esters 1 in almost quantitative yield are reduced selectively with magnesium in methanol and subsequently dealkoxycarbonylated to give protected ß-keto aldehydes 4 high yields.Keywords
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