• 1 January 1979
    • journal article
    • research article
    • Vol. 149  (5) , 667-670
Abstract
The weight change of 16 adult patients with cancer receiving total parenteral nutrition for an average period of 12 days was evaluated. The N to calorie ratio of the hyperalimentation fluid ranged from 1:144 to 1:235. The amount of nonprotein calories delivered was expressed as a multiple of the resting metabolic expenditure and patients were divided according to the following different rates of calories delivered/resting metabolic expenditure into 3 groups. The weight change in group 2 patients of +0.32 kg/day, was statistically different from that of group 1 patients, p < 0.01, but not from that of group 3 patients. The optimal hyperalimentation infusion rate to achieve weight gain in patients with cancer includes 50 nonprotein calories per kg/day as well as 1.5 g of amino acids/kg per day with a N to calorie ratio of 1:208.

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