Paraneoplastic cutaneous manifestations: concepts and updates*
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Open Access
- 1 February 2013
- journal article
- review article
- Published by FapUNIFESP (SciELO) in Anais Brasileiros de Dermatologia
- Vol. 88 (1) , 09-22
- https://doi.org/10.1590/s0365-05962013000100001
Abstract
The skin often signals systemic changes. Some neoplastic diseases that affect internal organs may trigger several cutaneous manifestations. Although these dermatoses are relatively unusual, the recognition of some typical paraneoplastic dermatoses may lead to the early diagnosis of a neoplasm and determine a better prognosis. In this review article, we discuss the paraneoplastic cutaneous manifestations strongly associated with neoplasms, which include acanthosis nigricans maligna, tripe palms, erythema gyratum repens, Bazex syndrome, acquired hypertrichosis lanuginosa, necrolytic migratory erythema, Leser-Trélat sign and paraneoplastic pemphigus. We also review the clinical manifestations of each condition and include updated knowledge on disease pathogenesis.Keywords
This publication has 37 references indexed in Scilit:
- Neoplastic/Paraneoplastic Dermatitis, Fasciitis, and PanniculitisRheumatic Disease Clinics of North America, 2011
- Abdominal Mass, Anemia, Diabetes Mellitus, and Necrolytic Migratory ErythemaDigestive Diseases and Sciences, 2011
- Cutaneous paraneoplasiaClinics in Dermatology, 2011
- Erythema gyratum repensJournal of the American Academy of Dermatology, 2011
- Paraneoplastic Syndromes: An Approach to Diagnosis and TreatmentMayo Clinic Proceedings, 2010
- Sign of Leser-Trélat with an adenocarcinoma of the prostate: a case reportCases Journal, 2009
- Sign of Leser-TrélatInternational Journal of Dermatology, 2008
- Clinical and pathologic findings of paraneoplastic dermatosesJournal of the American Academy of Dermatology, 2006
- Paraneoplastic dermatosesPublished by Elsevier ,2005
- Cutaneous markers of internal malignancy. I. Malignant involvement of the skin and the genodermatosesJournal of the American Academy of Dermatology, 1993