Alteration in Fibroblasts Treated with Steroids in a Perfusion Chamber.
- 1 May 1955
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 89 (1) , 146-150
- https://doi.org/10.3181/00379727-89-21741
Abstract
The response of chick and mouse fibroblasts to adrenal and non-adrenal steroids was studied in a perfusion chamber. Desoxycorticosterone and steroids closely related to it caused great increase in the size of the cells. The nucleus and heterochromatic material within the nucleus showed particularly great increase in volume. There was an increase in the number of mitochondria and a tendency to lay down large numbers of fibers.Keywords
This publication has 5 references indexed in Scilit:
- THE INFLUENCE OF CORTISONE UPON GRANULATION TISSUE AND ITS SYNERGISM AND ANTAGONISM TO OTHER HORMONESAnnals of the New York Academy of Sciences, 1953
- Selective Damage to Fibroblasts by Desoxycorticosterone in Cultures of Mixed TissuesScience, 1951
- Reversible Inhibition of the Beat in Heart Fragment Tissue Cultures by DesoxycorticosteroneExperimental Biology and Medicine, 1950
- THE EFFECTS OF THE HYPOPHYSIS, THYROID, SEX STEROIDS, AND THE ADRENAL CORTEX UPON GRANULATION TISSUE1950
- Effect of Cortisone on Production of Granulation Tissue in the Rabbit.Experimental Biology and Medicine, 1949