Influence of Exercise upon Serum Factors and its Secondary Effect on Glucose Utilization by the Resting Muscle

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Abstract
The aim of the present study was to investigate the existence of a transferable "exercise factor" which facilitates glucose transport. Rat hemidiaphragms were incubated either in rat plasma obtained from fasted donors or in rat plasma which previously was used as perfusate for a resting hind limb preparation, or in rat plasma which was perfused during electrical stimulation the hind limb. A transferable "exercise factor" could not be demonstrated; rather the "insulin-like activity" became progressively reduced, in plasmas previously perfused through resting or electrically stimulated muscle preparations. 1 This work was supported by Grant Number U-1960 from the Health Research Council of the City of New York.

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