The Total Complement Activity of Synovial Fluid in Juvenile forms of Arthritis

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Abstract
Summary The total complement activity of synovial fluid was determined in 47 patients with various forms of juvenile arthritis. The lowest complement values of the synovial fluid were found in patients with juvenile rheumatoid arthritis (JRA). The significance of various correlations in JRA — the complement activity of synovial fluid correlated inversely with both the age at onset and the rheumatoid factor titres — with regard to pathogenesis and the possibility that juvenile as well as adult RA might be a heterogeneous group of diseases, remains obscure. Observations made support the idea that oligo-arthritis is a condition essentially distinct from RA.