Radiologic diagnosis of oat cell cancer in a high-risk screened population.

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Abstract
A screening program of 10,040 cigarette-smoking men over 45 yr of age was undertaken to achieve earlier diagnosis, thereby increasing the cure rate, of oat cell lung cancer. Of the 155 men who had lung cancer, 27 (17%) had confirmed oat cell cancer. Only 1 case was diagnosed at the 1st examination. The other 26 cases (called incidence cancer) were diagnosed by subsequent examinations. In 24 of the 26 patients, the tumor was not found until it was advanced (Stage III); of these patients, only one is alive at 21 mo. follow-up. Two tumors were diagnosed as oat cell carcinoma at an early stage (Stage I); both patients are alive with no evidence of disease at 7 and 24 mo. The screening program used in this study did not succeed in detecting oat cell cancer at an early stage.

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