Novel Synthesis of 3-Fluoro-1-Aminoadamantane and Some of its Derivatives
- 1 November 1988
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 18 (16-17) , 1967-1974
- https://doi.org/10.1080/00397918808068263
Abstract
The title compound, 3-fluoro-1-aminoadamantane, isolated as the hydrochloride, has been synthesized in a three-step reaction sequence which is both convenient and rapid. Three derivatives of the amine, 3-fluoro-1-(N-adamantyl)-p-toluenesulfonamide, 3-fluoro-1-(N-adamantyl) benzamide, and 3-fluoro-1-methyl-(N-adamantyl) carbamate, have also been prepared. All compounds were characterized by the usual methods.Keywords
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