En route to supramolecular functional plasticity: artificial β-barrels, the barrel-stave motif, and related approaches
- 22 March 2001
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Chemical Society Reviews
- Vol. 30 (3) , 158-167
- https://doi.org/10.1039/b008101i
Abstract
This review emphasizes recent or pertinent efforts to create functional plasticity with artificial barrel-stave supramolecules and related motifs. On the structural level, a summary of engineered, de novo designed, and artificial β-barrels beyond peptide chemistry is followed by representative α-helix bundles and barrel-stave supramolecules comprising oligonucleotides, inorganic architecture, and organic barrel-stave ion channel models. On the functional level, selected examples are given to highlight divers aspects of molecular recognition, translocation, and transformation that are currently accessible with artificial barrel-stave supramolecules.Keywords
This publication has 0 references indexed in Scilit: