Association of the androgen receptor gene (AR) with ADHD and conduct disorder
- 1 May 1999
- journal article
- research article
- Published by Wolters Kluwer Health in NeuroReport
- Vol. 10 (7) , 1589-1592
- https://doi.org/10.1097/00001756-199905140-00036
Abstract
THE male predominance of externalizing behaviors suggests that the X-linked androgen gene might be involved. Since the shorter alleles of the CAG and GGC polymorphisms of the AR gene are associated with increased gene expression we sought to determine whether they were also associated with externalizing behaviors. We examined 302 subjects consisting of Tourette syndrome probands and controls. ANOVA showed a significant association between the AR haplotypes and ADHD (p pKeywords
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