In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of sparfloxacin

This publication has 24 references indexed in Scilit:

• The role of P‐glycoprotein in blood‐brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (−/−) and mdr1a (+/+) mice
  British Journal of Pharmacology, 1999
• The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.
  Journal of Clinical Investigation, 1998
• The Place of Quinolones in Everyday Clinical Practice
  Chemotherapy, 1996
• Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.
  Journal of Clinical Investigation, 1995
• Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
  Published by Elsevier ,1994
• Quantitative microdialysis under transient conditions
  Analytical Chemistry, 1993
• Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro
  Life Sciences, 1990
• Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein.
  Journal of Histochemistry & Cytochemistry, 1989
• Pharmacokinetic Disposition of Quinolones in Human Body Fluids and Tissues
  Clinical Pharmacokinetics, 1989
• Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability
  Journal of Medicinal Chemistry, 1980