Photoreceptive net in the mammalian retina
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Open Access
- 1 January 2002
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 415 (6871) , 493
- https://doi.org/10.1038/415493a
Abstract
We have discovered an expansive photoreceptive 'net' in the mouse inner retina, visualized by using an antiserum against melanopsin, a likely photopigment1,2. This immunoreactivity is evident in a subset of retinal ganglion cells that morphologically resemble those that project to the suprachiasmatic nucleus (SCN), the site of the primary circadian pacemaker3,4. Our results indicate that this bilayered photoreceptive net is anatomically distinct from the rod and cone photoreceptors of the outer retina, and suggest that it may mediate non-visual photoreceptive tasks such as the regulation of circadian rhythms.Keywords
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