Activation of the Akt/FKHRL1 Pathway Mediates the Antiapoptotic Effects of Erythropoietin in Primary Human Erythroid Progenitors
- 18 August 2000
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 275 (1) , 16-19
- https://doi.org/10.1006/bbrc.2000.3266
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Phosphatidylinositol 3-Kinase Is Involved in the Protection of Primary Cultured Human Erythroid Precursor Cells From ApoptosisBlood, 1999
- Insulin Stimulates Phosphorylation of the Forkhead Transcription Factor FKHR on Serine 253 through a Wortmannin-sensitive PathwayJournal of Biological Chemistry, 1999
- Phosphorylation of the Transcription Factor Forkhead Family Member FKHR by Protein Kinase BJournal of Biological Chemistry, 1999
- Protein Kinase B (c-Akt), Phosphatidylinositol 3-Kinase, and STAT5 Are Activated by Erythropoietin (EPO) in HCD57 Erythroid Cells But Are Constitutively Active in an EPO-Independent, Apoptosis-Resistant Subclone (HCD57-SREI Cells)Blood, 1999
- Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription FactorCell, 1999
- Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activationBiochemical Journal, 1998
- Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factorGenes & Development, 1998
- Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene SubfamilyGenomics, 1998
- daf-16 : An HNF-3/forkhead Family Member That Can Function to Double the Life-Span of Caenorhabditis elegansScience, 1997
- The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegansNature, 1997