Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening
- 1 February 2009
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 19 (3) , 589-596
- https://doi.org/10.1016/j.bmcl.2008.12.065
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Kinetic and Mechanistic Analysis of Trypanosoma cruzi Trans-Sialidase Reveals a Classical Ping-Pong Mechanism with Acid/Base CatalysisBiochemistry, 2008
- Rational drug design in parasitology: trans-sialidase as a case study for Chagas diseaseDrug Discovery Today, 2008
- The future of Chagas disease controlTrends in Parasitology, 2006
- Chemotherapy of trypanosomiases and leishmaniasisTrends in Parasitology, 2005
- A Sialidase Mutant Displaying trans-Sialidase ActivityJournal of Molecular Biology, 2005
- Inhibition of Microbial Sialidases - What has Happened Beyond the Influenza Virus?Current Medicinal Chemistry - Anti-Infective Agents, 2004
- Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-SialidaseStructure, 2004
- Structural basis of sialyltransferase activity in trypanosomal sialidasesThe EMBO Journal, 2000
- Mediation of Trypanosoma cruzi invasion by sialic acid on the host cell and trans-sialidase on the trypanosomeMolecular and Biochemical Parasitology, 1993
- A novel cell surface trans-sialidase of trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cellsCell, 1991