S-100 Protein in Guinea Pig Brain during Prenatal Development

Abstract
Nervous tissue-specific S-100 protein was quantified immunologically in maturing cerebrum, cerebellum and brain stem of guinea pigs during prenatal development. It was found to accumulate in its membrane-bound (pentanol-extractable) form concomitant with the accumulation of the water-soluble S-100 during development, indicating an ability of membranous structures to incorporate S-100 already during development.

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