Assessment of specimen fixation in a surgical pathology service.
Open Access
- 1 June 1992
- journal article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 45 (6) , 546-547
- https://doi.org/10.1136/jcp.45.6.546
Abstract
The quality of specimen fixation was examined within a routine diagnostic histopathology service. For each specimen the adequacy of fixation was assessed and the transit time between operating theatre and the laboratory was measured. Preliminary fixation was found to be inadequate in 25% of specimens and some form of manipulation to assist fixation was required in 36% of specimens. The mean transit time was 22 (SD 10.7) hours. Specimen fixation and transport are additional factors to consider in quality assurance of histopathology.Keywords
This publication has 9 references indexed in Scilit:
- Is the grading of breast carcinomas affected by a delay in fixation?Virchows Archiv, 1991
- Audit of turn-around times in a microbiology laboratory.Journal of Clinical Pathology, 1991
- Royal College of Pathologists' accreditation pilot study: a year later. The College Audit Steering Committee.Journal of Clinical Pathology, 1991
- Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some, neoplasmsThe Journal of Pathology, 1990
- Specimen transport audit.Journal of Clinical Pathology, 1990
- Does delay in fixation affect the number of mitotic figures in processed tissue?Journal of Clinical Pathology, 1990
- Royal College of Pathologists' United Kingdom pilot study of laboratory accreditation. The College Accreditation Steering Committee.Journal of Clinical Pathology, 1990
- The effects of progressive formaldehyde fixation on the preservation of tissue antigensPathology, 1989
- III.—THE RATE OF PENETRATION OF FIXATIVESJournal of the Royal Microscopical Society, 1941