Potassium and anaesthesia
- 1 March 1993
- journal article
- review article
- Published by Springer Nature in Canadian Journal of Anesthesia/Journal canadien d'anesthésie
- Vol. 40 (3) , 227-246
- https://doi.org/10.1007/bf03037035
Abstract
Potassium is the principle intracellular ion, and its concentration and gradients greatly infuence the electrical activity of excitable membranes. Because anaesthesia is so intimately involved with electrically active cells, potassium concentrations in surgical patients have received considerable attention in diagnostic and therapeutic applications. With the ongoing evolution in the indications for potassium, it is important to review the role of potassium in cellular activity, in storage and regulation, in diseases that alter potassium homeostasis, and in the therapeutic implications of perioperative alterations of potassium concentration. A rational approach to abnormal potassium values and the use of potassium in the operating room is sought, based on a physiological understanding of risks and benefits. Le potassium représente l’ion intracellulaire prédominant. Sa concentration et ses gradients ont une action primordiale sur l’excitabilité électrique des membranes. Comme l’anesthésie ellemême influence cette activité cellulaire, la kaliémie du malade chirurgical attire une attention considérable par ses applications diagnostiques et thérapeutiques. En facede l’évolution constante de ses indications, il est important de réviser le rôle du potassium sur l’activité cellulaire, son storage et sa régulation dans les états où l’hémostase du potassium est altérée, et les conséquences thérapeutiques de ces variations. Une attitude rationelle en regard des concentrations anormales de potassium et son utilisation en salle d’opération est recherchée tout en tenant compte des risques et des bénéfices.Keywords
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