Hemin-binding property of Porphyromonas gingivalis outer membranes
- 1 January 1991
- journal article
- Published by Oxford University Press (OUP) in FEMS Microbiology Letters
- Vol. 77 (1) , 45-49
- https://doi.org/10.1016/0378-1097(91)90011-x
Abstract
The present study indicates that the outer membranes of Porphyromonas gingivalis have a high affinity for hemin, an essential growth factor for this suspected periodontal pathogen. The hemin-binding property appears to be mediated by the lipopolysaccharides, particularly the lipid A region. It is suggested that this binding mechanism may be important for the growth and establishment of P. gingivalis in environments with a low hemin content such as periodontal pockets.Keywords
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